New or worsening peripheral neuropathy may well require a diminished dose or altered dose agenda (see Dosage Modification)
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This is not a whole listing of achievable Uncomfortable side effects. In case you recognize other consequences not detailed higher than, Speak to your medical professional or pharmacist.
bortezomib will raise the stage or influence of tinidazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
This medication may be prescribed for other utilizes; question your doctor or pharmacist for more information.
The therapeutic dose of bortezomib is individualized in Every client to avoid overdose. Lethal outcomes transpired in individuals subsequent the administration of greater than two times the advisable therapeutic dose of bortezomib. The signs and symptoms from overdose bundled the acute onset of symptomatic hypotension and thrombocytopenia. As there isn't a known antidote for bortezomib overdosage, monitoring of very important indications and correct supportive care ought to be initiated when drug overdosage is suspected.
Contemplate starting up SC cure for clients with preexisting or at high danger of peripheral neuropathy
cannabidiol will raise the level or influence of bortezomib by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Closely. Contemplate decreasing the dose of delicate CYP2C19 substrates, as clinically acceptable, when coadministered with cannabidiol.
Make sure you see your health treatment Specialist To find out more regarding your precise health care issue and the use of this drug.
bortezomib increases levels of eliglustat by affecting hepatic enzyme CYP2D6 metabolism. Contraindicated. If coadministered with strong or average AXL-IN-13 CYP2D6 inhibitors, reduce eliglustat dose from eighty four mg BID to eighty four mg at the time day by day in in depth and intermediate metabolizers; eliglustat is contraindiated if robust or moderate CYP2D6 inhibitors are presented concomitantly with potent or moderate 3'-cGAMP sodium CYP3A inhibitors.
eslicarbazepine acetate will raise the stage or impact of bortezomib by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Keep an eye on.
rifampin will decrease the level or impact of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
etravirine will lower the extent or outcome of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
Symptom Administration Lots of individuals residing with cancer working experience nausea, Retene diarrhea along with other indications from their therapy or condition.